Exercise and Diet Intervention: A lifestyle mediated approach for modern lifestyle affected Circadian Clock
The negative effect of the disrupted central circadian clock on our metabolic and physiological processes has been explored in the past. The impact of Diet and Exercise on this disrupted cycle has been reviewed by Parr and colleagues (2019) in their manuscript entitled, “A Time to Eat and A Time to Exercise” in the Exercise and Sport Sciences Reviews journal. A brief summary of their accepted article that was ahead-of-print status is as below:
Objective:
To study the effect of meal timings and exercise regime on reducing the harmful effects of disrupted circadian biology.
Methodology:
As findings in the mentioned area are limited, the existing four studies with small subjects have been reviewed.
Findings:
Daily exercise along with a healthy dietary approach is the most suggested way to prevent innumerable non-communicable diseases. Time-Restricted Eating (TRE) wherein energy consumption is limited to less than 10 hours has shown a positive effect on obesity and metabolic disorders. Studies concluded that TRE affects the circadian cycle and regulates hormone secretion and metabolism, increases ketone bodies, and circulating FFA. Exercise training helps in an overall positive response by regulating lipid profile, improving glucose tolerance, uptake of FFA by muscle and liver, and also regulating appetite by increasing satiety response to a meal. TRE has a similar outcome as exercise training but exercise additionally helps in remodeling almost every organ/ part of the body. For individuals unable to perform the physical activity due to medical condition, TRE can be suggested as a strategy to improve metabolic health. Exercise snacking with 3 x 10 bouts after meals have improved glycemic control in Type 2 Individuals than continue 30 min walk.
Limitations:
As per the author’s view, long-term intervention studies with a large sample size are required to give an elaborated understanding of existing findings.
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