Dr. Rajeev Chawla – Guest Editor for June 2021
I am delighted to be the Guest Editor for Metabolic Health Digest’s June 2021 issue. Ever since COVID-19 pandemic has begun, several variants have been known and various researches are coming in with regards to analyzing the efficacy of the vaccines.
On another note the prevalence of Obesity and PCOS is seen to be surging which is leading to a rise in infertility issues. But a new approach could be adopted apart from the gold standard method of “weight loss”. Administration of GLP-1RA alone or in combination with metformin could result in improvement of various profiles such as those of insulin resistance, testosterone reduction etc.
Diabetic complications exist in a loop where un-managed or erratically regulated blood sugar levels lead to co-morbidities (CKD) and eventually result in cardiovascular events. Therapies that have kidney-protective and cardio-protective properties have been reported to prevent and may result in the prevention of downstream conditions and improve overall outcomes in high risk patients.
This month, I am excited to feature Finerenone, a novel selective non-steroidal mineralocorticoid receptor antagonist and also the combined treatment of cagrilintide and semaglutide on obesity was similarly found to be helpful. Apart from this, you will find late breaking trials from the recently concluded scientific sessions of the American Diabetes Association including some latest data on Twincretins- Surpass & AmplitudeO cardio vascular outcome trial.
Practice Corner like every month will feature 3 exciting case … one on remission of diabetes & hypertension following bariatric surgery, one on use of GLP1 in PCOS & effective optimization of coformulation insulin in practice.
Metabolic Health Digest aspires to showcase latest research findings for the medical community. The discussion of various studies on this panel can help stay updated with latest clinical practices and thereby can aid in refining the treatment outcome of the patients in the long run.